Connect with us

Tech

Better Organ Preservation Through Advances in Cryopreservation

Published

on

Better Organ Preservation Through Advances in Cryopreservation

Saffron Bryant

cryoprotector illustration

The development of cryopreservation technology has made it possible to rapidly advance in reproductive technologies, stem cell therapy, and even save species from extinction.

However, as part of the cryopreservation process, agents are added to protect cells from damage and dehydration during the freezing process. Physical Organization.

The two main agents used in cryopreservation in recent decades are dimethyl sulfoxide and glycerol, both of which are toxic.

These agents are also unsuitable for hundreds of cells, and so far preservation of organs and tissues has not been achieved. Because of this, up to 60% of donor hearts and lungs are discarded.

“We have a lot of organs, but most of them are just thrown away,” says RMIT’s Saffron Bryant, principal investigator on the new study. “We only have a few hours to transfer an organ from a donor to a recipient.”

The research team analyzed the effectiveness of eutectic solvents as cryoprotectants. They compared it to six different solvents in mammalian cells and tested thermal properties, toxicity, and permeability in four mammalian cell types, including skin and brain.

The researchers determined that a eutectic solvent made from proline and glycerol was the most effective cryoprotectant. effective for mammalian cells.

This solvent was also less toxic than when its components were used alone, highlighting the potential for optimizing cryopreservation using combined agents.

These cryoprotective agents can even be tailored to specific cell types and thousands of combinations could potentially be developed.

The team also did increase incubation time cells with this new cryopreservative, according to the results of the study, published no Journal of Chemistry of Materials B.

See also  The Iphone 12 will not spur massive updates — here’s why

“Incubating these cells with cryoprotectant at 37°C for several hours before freezing and maintaining their viability is an important step in organ and tissue storage,” says Bryant.

“This means that we can expose organs to cryoprotectants long enough for them to penetrate deeper layers of the organ without causing damage,” he says.

s o 1850 people on the waiting list for organ transplants in Australia and more than 100,000 people awaiting transplants in the US, these new cryoprotectants could help keep donor organs viable for years, not hours.

“We have a long way to go in our studies because we only looked at individual cells, and for organs it is a much more complex process,” adds Bryant.

“But if we can create this approach to storing organs, we can eliminate their shortage – no queue“, he concludes.

ZAP //

Continue Reading
Click to comment

Leave a Reply

Your email address will not be published. Required fields are marked *

Tech

The Earth was hit by the solar wind at a speed of 600 kilometers per second

Published

on

Ilustração vento solar a atingir a Terra

We really do not live in peacetime. There is talk of extreme droughts, wars, fires, economic crises, and even in space, our star insists on whipping the planet with solar winds that surprise scientists who study these phenomena. The most recent case was a solar storm that hit Earth over the weekend. Without warning, the winds “hit” our planet in a completely unexpected way.

On Sunday, a stream of solar wind hit the Earth’s magnetic field, the speed of which reached more than 600 kilometers per second.

As we already mentioned, our star is in its 25th cycle, and when it began, the researchers left an alert that this new 11-year period will not be as calm as the last one, which ended at the end of 2019.

Some events, such as the M4.4 class solar flare or the X-class flare that occurred in 2021, show ongoing activity on our star. By the way, we saw that a G1 class storm was predicted last week. According to NOAA, this event, which reached us on August 3, did not cause any problems and its origin was associated with a hole in the sun. as explained here.

Image of auroras caused by solar winds hitting our atmosphere

The Earth received an unexpected impact at a speed of more than 600 kilometers per second

Without warning, a strong gust of solar wind hit Earth last Sunday. While it's not all that alarming - solar storms often hit our planet and cause spectacular auroras - it's strange that this storm was completely unexpected.

This event was not in the forecast, so the auroras that arose came as a surprise.

informed SpaceWeather.

The solar wind occurs when a stream of high-energy particles and plasma can no longer be held by the Sun's gravity and erupts towards the Earth. Because how our Sun works is still largely unknown, these emissions are thought to come from large, bright spots on the Sun known as "corona holes." These events taking place on a star have been observed for a long time, and there is a lot of observational work being done here on Earth.

Picture of two holes in the sun

Through this attention to holes, scientists have been able to create "predictions" of space weather. They can already predict when these solar storms or solar flares, also known as coronal mass ejections (CMEs), will come our way. Plus, you can already see how powerful they will be.

However, this does not mean that the Sun does not surprise us and hit us without warning, as it did over the weekend.

But how was this effect of solar winds on our planet discovered?

Earlier Sunday, NASA's Deep Space Climate Observatory (DSCOVR) observed solar wind light streams that increased significantly and unexpectedly throughout the day. The cause of this solar storm is still unknown, but SpaceWeather suggests it may have been an early arrival of the solar wind, which is expected to come from an equatorial hole in the Sun's atmosphere two days later. Or it could be a lost coronal mass ejection (CME).

The inhomogeneity of the solar wind data at 00:45 UT on August 7 suggests a shock wave embedded in the solar wind.

Today, the active sun produces so many small explosions that it is easy to ignore the faint coronal ejections heading towards Earth.

This is how he described the SpaceWeather service.

It is interesting to note that as of today, August 9, the high-speed solar wind continues to beat the Earth's magnetic field, with records showing speeds as high as 551.3 kilometers per second. This new "attack" on our natural shield began this morning at 5 am.

The good news is that the solar wind is not harmful to us here on Earth. This is because we are safely protected by our planet's atmosphere.

However, when the "collision" is strong, our technologies can suffer from it. That's why they talk about it and we've seen it before problems with telecommunications satellites and, in extreme cases, with electrical networks.

Solar storm classified as G2

These winds have been classified as a moderate G2 solar storm - storms are classified as G1 at the bottom of the scale to G5 which is a powerful solar storm.

According to space meteorology, G2 storms can affect high-latitude energy systems and could impact spacecraft orbit forecasts.

In fact, it is already becoming a routine. This is due to the fact that this year there are especially many such events. However, as mentioned above, these 11 years of the 25th solar cycle will not be peaceful.

See also  E3 2021: What To Expect On The First Day Of The Event This Saturday (Dec 6)
Continue Reading

Tech

Scorpion: New Belfast Evo and Evo Carbon Retro Helmets

Published

on

Korean helmet manufacturer Scorpion is best known for its sporty modular touring and aggressive style urban helmets. But the brand also has a vintage helmet that has been on the market for half a dozen years: the Belfast Jet.

This year, Scorpion decided to update its line of equipment with new retro helmets Belfast Evo and Belfast Evo Carbon.

In appearance, the Evo versions are of course very close to the previous versions, as it is a round pendant in a very classic style. But inside the Ultra-TCT fiberglass shell, things have changed as the helmet now complies with the ECE R22-06 standard.

The Belfast Evo features a hypoallergenic, removable and washable Kwikwick 2 liner, Kwikfit goggle slits, hand-stitched faux leather lining and a chin strap with micrometric buckle. There’s also a Speedview anti-fog sunscreen. The set is very light, about 1100 grams according to the manufacturer.

The Evo Carbon variant features an even lighter weight of 950 grams and the use of Kiwkwick 3 interior trim. Its price is also significantly higher.

Scorpion is offering its Belfast Evo jet from €169.90 in a single seat version and a carbon version starting at €299.90.

Selling points: JC Motos, Caparicapeles, AdvSpirit, Motovest

See also  The Iphone 12 will not spur massive updates — here’s why
Continue Reading

Tech

Samsung plans to release a tablet with a folding screen

Published

on

Samsung plans to release a tablet with a folding screen

BUT Samsung has already made it clear that it intends to continue betting on foldable phones, which will include the company’s new Galaxy Z Fold 4 and Galaxy Z Flip 4 models this week.

Apart from wanting to contribute to the foldable mobile phone category, a South Korean tech company is also known to be developing a foldable screen tablet. Who says this is the Ice Universe page on the Chinese social network Weibo (via Android Headers), referring to the fact that the tablet in question will be called the Galaxy Tab Fold.

The page in question suggests that the Galaxy Tab Fold will be announced at the same Galaxy Tab S9 launch event that Samsung usually holds in the first quarter of the year.

It is possible that the presentation of these two tablets will take place in early 2023, but given that we had to wait two years between the Galaxy S7 (2020) and Galaxy S8 (2022), there is also a possibility that the Galaxy Tab Fold and Galaxy Tab S9 will appear only in 2024.

Read also: Release date, price and colors of Samsung cordless phones

Always be the first to know.
6th year in a row Consumers Choice and Five Star Award for Online Press.
Download our free app.

Apple Store Download

See also  SpaceX Dragon successfully docked with the International Space Station
Continue Reading

Trending