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Blind man partially regains vision after 40 years of innovative therapy – world



Blind man partially regains vision after 40 years of innovative therapy - world

A 58-year-old blind man partially regained his vision after injecting algae proteins into his eye as part of a scientific study. 40 years ago, the Frenchman was diagnosed with retinitis pigmentosa, a genetic disorder that causes vision loss, and can now distinguish between nearby objects and navigate the street using stimulating glasses.

The study was published this Monday in a scientific journal. Nature Medicine and reports the progress of vision in a person receiving optogenic therapy in which proteins from algae are used to control cells within the eye. For the first time, this technique, in which teams from the USA, Switzerland and France participated, proved to be successful.

These microorganisms, scientifically named Canalrodopsin or channel rhodopsins are sensitive to light. They change their behavior when stimulated by light to move towards it, and for this reason they have shown favorable results when injected into the patient’s eye, which initially had limited visual acuity for the perception of light.

In statements to BBCProfessor Botond Rosca, one of the researchers in charge of the research at the University of Basel, said that “the data obtained prove that the use of optogenetic therapy for partial restoration of vision is possible.”

Before and after the injection, the patient underwent eye examinations, general examinations, and electrocardiograms to stimulate the regeneration of destroyed cells to evaluate the retinal anatomy several times and see if there was intraocular inflammation or any adverse factors.

This was followed by tests to understand the response of proteins to light stimulation using stimulating glasses. Initially, the patient did not notice any changes in vision, however, seven months after starting vision training, the patient began to report signs of improvement in vision when using glasses that were retained.

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The tests focused on three parameters: both eyes open without light-stimulating glasses (natural binoculars); one eye is closed and the other is open without glasses (natural monocular) and one eye is closed and the other is opened with the stimulus of the glasses (stimulated monocular).

In the first test, a man had to perceive, locate, and touch an object placed on the surface of a white table at a distance of about 60 centimeters. The patient showed positive results only in the stimulated monocular mode, with a success rate of 92% of attempts. This figure depended on the size of the object and was higher when it was large.

In the second test, which included perceiving, counting and locating more than one object in a stimulated monocular, the patient had a 63% success rate for perception and counting. On the spot, the rate was 58%.

When he went out for a walk, the patient said that he saw pedestrian crossings and the road, including counting white stripes. In daily life, he also reported discriminating between common objects such as plates, mugs, doors and corridors, but only when he used light-stimulating glasses.

The study concluded that the percentage of correct assessments was significantly higher under stimulated monocular conditions (41%) than in vivo binoculars and monoculars (5.8%). Thus, this is the first scientific evidence that algae protein injection, combined with optogenic therapy and the use of light-stimulating glasses, produces a visual perception that allows the patient to be guided, to perform a visual task, and to reach the target.

Optogenetic therapy is a technique that combines light, genetics, and bioengineering to study and activate neural circuits. Over the past decades, he has presented significant advances in identifying the causes of diseases and indicating treatment options. However, its use in humans is still limited, but promising, as it allows you to select certain cells without touching others around them, that is, without causing side effects compared to the methods of electrical stimulation that are currently used.

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‘My power is really low’: NASA’s Mars Insight rover prepares to launch from the Red Planet



NASA Lander InSight He has delivered what may be his last message from Mars as he embarks on a historic mission to uncover the secrets of the Red Planet’s interior.

In November, the space agency warned that the probe could be running out of time as dust continued to condense and stifle InSight’s power.

“Spacecraft power generation continues to decline as windblown dust accumulates on solar panels,” NASA said in a statement. Update November 2. “The end is expected to come in the coming weeks.”

message shared NASA The InSight Twitter account tweeted on Monday: “My power is very low so this might be the last photo I can upload. Don’t worry about me: my time here has been productive and uneventful. If I can keep talking to my mission team, I will—but I will.” Subscribe here soon. Thank you for staying with me.”

My power is very low, so this might be the last photo I can upload. But don’t worry about me: my time here has been productive and uneventful. If I can keep talking to my mission team, I will, but I’ll sign here soon. Thank you for staying with me.

— NASA InSight (@NASAInSight) December 19, 2022

A geologist robot armed with a hammer and a seismograph first reached the barren expanse of Elysium Planitia in November 2018.

Since then, she has carried out geological excavations, taking the first measurements of earthquakes with a high-tech seismometer placed right on the surface of Mars.

Last month, the solar-powered car released an update to remind us of its time in space.

“I was lucky to live on two planets. Four years ago I made it safely to the second one, much to the joy of my family at first. Thanks to my team for taking me on this journey of discovery. I hope I can be proud of you.”

According to the published mission, Insight has measured more than 1,300 seismic events since it was published, and more than 50 of them had signals clear enough for the team to extract information about their location on Mars. Results.

The probe’s data also provided detailed information about Mars’ interior, liquid core, surprisingly variable remnants beneath the surface of an extinct magnetic field, climate and seismic activity.

old for Its launch in 2018NASA Chief Scientist Jim Green said the mission was “fundamental to understanding the origins of our solar system and how it became what it is today.”

NASA will not declare the mission complete until Insight confirms the arrival of two spacecraft orbiting Mars that are relaying their information back to Earth.

In 2018, the veteran rover announced the capabilities end of his 15 year stay Sending an incomplete photo of the Valley of Perseverance.

A severe dust storm darkened the sky around the solar-powered rover, shattering the sun and leaving behind a dark image with white spots due to camera noise. The transmission is interrupted before the complete image can be transmitted.

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What’s new on February 7, 2023



OnePlus 11 5G Buds Pro 2 evento

Being very close companies, OPPO and OnePlus have decided to create a new partnership, with the latter being a pioneer in the market. It has become the representative of the best smartphones in the group, and this will be seen very soon.

Proving this, OnePlus has announced that it will have news soon. The following brand assets will be announced on February 7, 2023. We are talking about OnePlus 11 5G and Buds Pro 2.

In recent years, OnePlus has been showcasing new hardware in an attempt to find a new place in the market. The brand has not always seen its full potential, betting on mid-range or entry-level smartphones.

The situation is changing, and the novelty will go on sale in early 2023, February 7. It is on this day that the new OnePlus 11 5G will be presented with all the expected news. We definitely have the new Qualcomm Snapdragon 8 Gen 2 SoC here. There's still 16GB of storage left and 256GB of onboard storage.

OnePlus 11 5G Buds Pro 2 events

It is expected that he will receive a 6.7-inch OLED display with a resolution of 1440p and a frequency of 120 Hz. In the field of photography, we will have an important change: a 50 MP main camera, a 48 MP ultra wide-angle camera and a 32 MP telephoto lens with 2x zoom. For selfies and video calls, you'll have a 16-megapixel camera.

The photography partnership with Hasselblad will continue with OnePlus for fine-tuning and some additions. This alliance has brought important results for the best smartphones of the brand, guaranteeing the best photos in any situation.

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OnePlus 11 5G Buds Pro 2 events

In addition to the new OnePlus 11 5G, another brand new feature is also expected to arrive at the event. We're talking about the Buds Pro 2, which are solidifying an audio commitment that's becoming more of a reality. The brand promises "rich stereo quality sound with crystal clear clarity".

Stays like this marked by the beginning of February, another important novelty will enter the market. OnePlus wants to reclaim its place, and that will be the brand's bet for years to come. OnePlus 11 5G and Buds Pro 2 take the first step in this direction.

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New POCO Smartphone Seen in Certification May Debut Soon



New POCO Smartphone Seen in Certification May Debut Soon

According to information provided by Mukul Sharma, the unidentified POCO device can be identified by the model number 22127PC95I. Due to the fact that it was first seen online, the marketing name of this equipment is still a mystery.

POCO has not launched new mobile devices, including smartphones, to the market for some time now. On the other hand, several POCO smartphones such as POKO X5 and X5 Pro have been spotted on various certification sites, suggesting that the company will release these products soon. Today a new smartphone from the sub-brand xiaomi has been spotted on the BIS India website but the device does not have a name or any other details associated with it.

According to information provided by Mukul Sharma, the unidentified POCO device can be identified by the model number 22127PC95I. Due to the fact that it was first seen online, the marketing name of this equipment is still a mystery. It is possible that it will debut as a mid-range smartphone. The Bureau of Indian Standards (BIS) website, other than the model number of the smartphone, does not provide any additional information about the device. However, this seems to indicate that the product will be available in the Indian market very soon.

In other related news, POCO X5 5G has recently been seen on several certification sites including SIRIM in Malaysia, BIS in India and the US FCC. According to various sources, it is possible that this is a renamed or modified version Redmi Note 12 5Gwhich was recently released in China.

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It is supposed to be equipped screen 6.67″ AMOLED display with 120Hz refresh rate and chipset Snapdragon 4 Gen 1 inside. Can run MIUI 13 based on android 12 and have LPDDR4x RAM in addition to UFS 2.2 storage. The front camera is rumored to be 8MP while the main rear camera will be 48MP with 2MP depth. May have the ability drums 5000 mAh and 33W fast charging support.

In addition POCO X5 Pro 5G has recently been seen on various sites dedicated to certification. The battery is said to have a capacity of 5000 mAh and can charge at 67W. It will come with MIUI 14 preinstalled and will support n5, n7, n38, n41, n77 and n78 network bands. 5G.

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